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Company has ‘largest IPO’ out of any Pitt spinout

Oncorus, a company spun out of the University of Pittsburgh, recently initiated an initial public stock offering, raising nearly $90 million as it enters clinical trials on its oncolytic virus cancer therapy. That amount is being called the “largest IPO of a Pitt spinout” by the University’s Innovation Institute.

The technology for the Cambridge, Massachusetts-based company was licensed from Pitt from the lab of Joseph Glorioso, professor of microbiology and molecular genetics in Pitt’s School of Medicine. Glorioso was one of the founders of Oncorus and is chair of the company’s scientific advisory board. The company, founded in 2016, had previously raised approximately $140 million in private investment.

“It’s great. It’s a substantial amount of money,” Glorioso said. “It’s really based on not only the technology within the company being tested in patients, but also other technologies that are very exciting and will be used to treat people with cancer.”

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Dimiter Stanchev Dimitrov named ‘Science Superhero’

Dimiter Stanchev Dimitrov, director of the Pitt Center for Antibody Therapeutics, was recently named one of 10 “Science Superheroes” by MediFind.

Dimitrov was recognized on the list as one of the first to discover neutralizing antibodies for the original SARS coronavirus in 2003. In the ensuing years, his team discovered potent antibodies against many other infectious diseases. His lab recently isolated the smallest biological molecule to date that completely and specifically neutralizes the SARS-CoV-2 virus, which is the cause of COVID-19.

The antibody center is housed within the Division of Infectious Diseases at Pitt and is a key component of the UPMC Immune Transplant and Therapy Center.

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LRDC scientists receive $900,000 grant to study robots in math classrooms

Erin Walker (pictured), associate professor in the School of Computing and Information and research scientist in the Learning Research and Development Center, has been named principal investigator for a $900,000 National Science Foundation grant to study the use of robots in middle school math classrooms.

Co-principal investigators on the grant are Diane Litman, professor of Computer Science and senior scientist in the LRDC; Timothy Nokes-Malach, associate professor of Psychology in the Dietrich School of Arts and Sciences and research scientist in the LRDC; and Adriana Kovashka, assistant professor in SCI.

Walker and colleagues will investigate the use of robots to support collaborative learning. When students work together with an intelligent tutoring system such as a robot, they are able to learn more and explain their reasoning while also building on each other’s ideas. Walker and colleagues will investigate if the robot’s gaze or gestures, combined with dialogue, can promote middle school students' collaborative interactions and lead to more math learning. The main goal of the project is to gain a better understanding of how robots can be integrated effectively in learning environments.

Walker also has recently received a Google AI 2020 Award for Inclusion Research with colleague Leshell Hatley, of Coppin State University in Baltimore. In this work, Walker and Hatley are collaborating on a project to develop a dialogue system for a culturally responsive robot.

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Heather Lyke elected president of Women Leaders in College Sports

Pitt Athletic Director Heather Lyke has been named president-elect of the Women Leaders in College Sports organization. Lyke will serve on a three-year executive track beginning this year.

Founded in 1979, Women Leaders in College Sports is the only nationally recognized collegiate professional membership organization whose mission is to develop, connect and advance women leaders working in intercollegiate athletics. With more than 3,500 members, the organization promotes the growth, leadership and success of women as athletics administrators, conference commissioners, professional staff, coaches and student-athletes.

In a release naming Lyke president-elect, along with new members of its board of directors and nominating committees, the organization highlighted Lyke’s leadership of Pitt Athletics, including her recruitment of new head coaches, rebranding of the University’s athletic marks and logos and unveiling of Pitt Studios.

Lyke served on the Women Leaders board of directors from 2014-2018.

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Margaret Rosenzweig wins nursing award for academic and clinical work

Margaret Rosenzweig, a two-time alumna and distinguished service professor in the School of Nursing, is the 2020 recipient of the Friends of the National Institute of Nursing Research’s President’s Award.

The award is given annually to a researcher who engages both academia and clinical practice partners.

Rosenzweig has been principal investigator on 15 studies addressing cancer survivorship, symptom management, end of life care and disparities among women with breast cancer. Her work has contributed to the understanding of racial differences in the completion of breast cancer treatment and the identification of geographic risk for higher breast cancer mortality.

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Pitt researchers to study gender-integrated training in military settings

The Neuromuscular Research Laboratory/Warrior Human Performance Research Center at the University of Pittsburgh was recently awarded $2 million from the U.S. Marine Corps to study gender-integrated recruit training.

The multi-institutional collaborative study will analyze combinations of gender-integrated training and make recommendations for models that integrate genders to the greatest extent possible while continuing to train Marines to established standards. Specifically, the study will address the sociological and physical training effects of increased gender integration and consider training models which maintain the same level of discipline, physical fitness, attention to detail and camaraderie.

“The Academic Study of U.S. Marine Corps Gender-Integrated Recruit Training will utilize a multistage mixed-method study design and address multidisciplinary evaluation questions through both a social science and human performance lens,” said co-principal investigator Mita Lovalekar, who is an associate professor in Pitt’s Department of Sports Medicine and Nutrition in the School of Health and Rehabilitation Sciences. “Our study will also assess musculoskeletal injury patterns between male and female recruits during entry level training which will extend upon our prior work identifying the financial and medical costs for these injuries and the negative impact on military readiness.”

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SHRS appoints four new associate deans

The School of Health and Rehabilitation Sciences recently named four faculty to new associate dean positions in an effort to address major school-wide initiatives.

  • David Beck, assistant professor and chair of the Department of Physician Assistant Studies, will take on an additional role as associate dean for interprofessional studies.

  • M. Kathleen Kelly, associate professor in the Department of Physical Therapy, will assume responsibilities as associate dean for academic outreach and advising. 

  • Thomas Platt, vice chair of the Division of Community Health Services and associate professor and director of Pitt’s Emergency Medicine program, has been named associate dean for academic partnerships.

  • Bernard Rousseau, professor and chair in the Department of Communication Science and Disorders, will serve as the associate dean for equity, inclusion and community engagement.

For each faculty leader’s role, visit the school’s page.

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Statistics’ Joshua Cape awarded NSF grant to study immigration and U.S. job market

Joshua Cape, assistant professor of Statistics in the Dietrich School of Arts and Sciences, together with collaborators at Johns Hopkins University, has received a $550,000 grant from the National Science Foundation for the proposal “Methods and Applications for Massive One-mode and Bipartite Social Networks.”

The NSF grant will enable Cape and his colleagues to develop new methods and modeling capabilities for large-scale network data. Using datasets from the Longitudinal Employer-Household Dynamics program at the U.S. Census Bureau, the project will examine the influence of immigration on the U.S. job market over time. The transdisciplinary research team consists of principal investigator Angelo Mele, co-principal investigators Lingxin Hao, Carey E. Priebe — all from Johns Hopkins University — and Cape.

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Wells Competition awards three healthcare startup teams

Three entries to the 10th annual Michael G. Wells Competition, hosted by the University of Pittsburgh’s Innovation Institute, won $5,000 prizes for their work toward healthcare innovation.

The winners included BioBulwark, a mesh implant that provides long-lasting prevention of infection superior to currently popular organic chemical coatings; Biocarpet, an endovascular device that can be shaped by heat to treat peripheral arterial disease occurring in small and complex anatomies, including lesions occurring across joints; and OPS, an endovascular device that provides oxygenated blood flow to critical abdominal organs to maintain organ health for transplant harvesting.

The competition usually awards grand prize winners $20,000, second-place winners $10,000 and third-place winners $5,000. The competition’s namesake, Michael G. Wells (pictured), said the decision to distribute prize money equally came from the judging panel determining that these teams could benefit from money and time to move their ideas along. Wells also said prize money that wasn’t given out will be awarded to teams early next year who have shown “demonstrable progress” in their respective projects.

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Web app for surgical, anesthetic scheduling wins Kuzneski Cup

ChangeOR took home the grand prize for the fifth annual Kuzneski Innovation Cup, hosted by the University of Pittsburgh’s Innovation Institute.

The project is a multi-platform web application that allows for the efficient delivery of real-time surgical and anesthetic scheduling information. The research is being led by Evan Lebovitz, an assistant professor in the Pitt’s Department of Anesthesiology and Perioperative Medicine, and Mark E. Hudson, UPMC Richard J. Kuwik endowed professor in the same department.

Second place was awarded to AI Smiles, an additive-manufactured denture that dramatically reduces cost, appointments and waste in dental settings. Third prize was awarded to NanoNares, a platform technology for pharmaceutical companies that develop respiratory drugs which experience high failure rates in clinical trials.

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More than 700 students participate in Pitt HR's annual Disability Mentoring Day

The Office of Human Resources held its annual Disability Mentoring Day in mid-October at Beaver Area High School.

The office partners with other University areas to provide mentoring to local high school students with disabilities. It focuses primarily on items like resume writing and interviewing. The office normally hosts the event on campus each year, with visits to Panther Central and Pitt Police, but this year it was held virtually.

Participants included 29 employers and more than 700 total students. They came from the city of Pittsburgh, the counties of Allegheny, Washington and Westmoreland, and 40 school districts.

“Our Pittsburgh region has always shown remarkable participation in this event, which has — and continues to get — high marks,” said Tom Armstrong, recruiter for veterans and individuals with disabilities in Pitt’s Office of Human Resources.

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Joel Philistin named new financial wellness program director

The Office of Admissions and Financial Aid (OAFA) and Student Affairs have jointly named Joel Philistin their financial wellness program director. Philistin started in the newly created position in September.

“Financial wellness represents being equipped with the knowledge, skills and resources to make informed financial decisions. The financial decisions that college students make today can impact them well beyond graduation. Our program goal is to give our students the tools to build a strong financial foundation for now and after graduation,” Philistin said.

Philistin came to Pitt from the College of the Mainland in Texas, where he served as a financial literacy educator and financial aid advisor from 2018 to 2020. There, he relaunched the college’s financial literacy program with an emphasis on classroom workshops and increasing financial aid applications; over two years, the number of students who applied for financial aid at the college increased by 3 percent.

Philistin also worked at Houston Community College where he helped develop an award-winning student loan debt series and launched several initiatives, including a food scholarship program and Hurricane Harvey emergency grant. Prior to his work in higher education, Philistin worked in the banking industry, first as a teller and then assistant branch manager, before earning a master’s degree in public administration with a focus on non-profit management.

Randall McCready, executive director of financial aid in OAFA, hopes the new position will engage students to learn more about their finances especially during a time of great economic uncertainty.

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Pittsburgh Supercomputing Center receives NSF grant for nerve cell research

The Pittsburgh Supercomputing Center, a joint research effort by the University of Pittsburgh and Carnegie Mellon University, recently received a $750,000 grant from the National Science Foundation, which will continue a lab-computer collaboration that accurately simulates communications between nerve cells and muscle cells. Stephen Meriney, professor of neuroscience in the Dietrich School of Arts and Sciences, is a principal investigator of the project.

The project has immediate applications in treating a type of neurological disease called Lambert-Eaton Myasthenic Syndrome (LEMS). It also offers fundamental insights into how nerve cells communicate with muscle cells in health and disease. LEMS is a neurological disease in which a person’s immune system attacks calcium channels, leading to a weaker communication between nerve and muscle, which causes weaker muscle contractions and an inability of patients to move and function normally.

In earlier work, scientists at the center and Pitt simulated the role of the calcium channels of the nerve-cell membrane in communication between nerve and muscle cells in frogs and mice. The work faithfully reproduced the nerve-to-muscle signaling differences seen in those species.

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Provost Cudd delivers presidential address to law and social philosophy association

Provost Ann Cudd delivered the presidential address at the October 2020 biannual conference of the American Section of the International Association for Philosophy of Law and Social Philosophy. The meeting, which focused on the topic of “Education, Inclusion and Justice,” gathered scholars from around the world for three days of intensive discussions.

Association membership includes philosophers, legal theorists, political scientists and economists with interests in probing issues about justice, society, the economy and democracy.

Cudd’s address was titled “After the Apocalypse: The Future of Higher Education.”

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Changfeng Tai receives $10.5 million DARPA award

Changfeng Tai, associate professor of urology and pharmacology in the University of Pittsburgh School of Medicine, was awarded $10.5 million from the Defense Advanced Research Projects Agency (DARPA) to develop a medical device that would help people who suffered spinal cord injuries.

Through the five-year award, Tai and his team will develop a fully implantable, wirelessly controlled and chargeable stimulator to restore three visceral functions including bladder, bowel and sexual functions for people with spinal cord injuries. Restoring these visceral functions remains a top priority for functional recovery in people with spinal cord injuries, and can dramatically improve the quality of life and prevent potential kidney failure caused by bladder-sphincter dyssynergia. The device would act similarly to how a pacemaker helps the heart pump blood, except it would be inserted under the skin in the lower back.

“This award is significant in the progress of this device,” said Tai. “The hope is that this will one day ease the burden that people with disabilities related to spinal cord injuries face every day, including military veterans. We will work with our collaborators to build a system that will allow for human clinical trial use.”

DARPA is a research and development agency of the United States Department of Defense responsible for the development of emerging technologies for use by the military. The award is part of DARPA’s BG+ program.

Four engineering faculty received CAREER awards in 2019-20

Four faculty in the Swanson School of Engineering received Faculty Early Career Development (CAREER) awards from the National Science Foundation during fiscal year 2019-20, bringing to 15 the number of the school’s faculty who have received the awards since 2016.

According to NSF, the CAREER Program is its most prestigious award in support of early-career faculty who have the potential to serve as academic role models in research and education and to lead advances in the mission of their department or organization.

The 2020 recipients include:

Takashi D-Y Kozai, assistant professor of bioengineering, received $437,144 for Uncovering the Impact of Traditional and Novel Chronic Stimulation Modalities on Neural Excitability and Native Neuronal Network Function.

Sangyeop Lee, assistant professor of mechanical engineering and materials science, received $500,000 for Machine Learning Enabled Study of Thermal Transport in Polycrystalline Materials from First Principles.

Jason Shoemaker, assistant professor of chemical and petroleum engineering, received $547,494 for Enabling Immunomodulatory Treatment of Influenza Infection using Multiscale Modeling.

Feng Xiong, assistant professor of electrical and computer engineering, received $500,00 for Scalable Ionic Gated 2D Synapse (IG-2DS) with Programmable Spatio-Temporal Dynamics for Spiking Neural Networks.

For more information about the research projects, go to the Swanson School of Engineering’s website.

Starzl documentary honored with Donate Life award

Burden of Genius,” a documentary that tells the story of Pittsburgh transplant pioneer and surgeon Thomas Starzl, was honored on Oct. 8 with the Donate Life Hollywood Inspire Award for motion pictures, television shows and documentaries that shed a positive light on organ donation.

Other recipients included NBC’s “New Amsterdam,” Showtime’s “Kidding” and Nova’s “Transplanting Hope.”

The Starzl documentary, co-produced by Carl Kurlander, a senior lecturer in Pitt’s Film and Media Studies Program, details the surgeon’s 60-year career, including the world’s first successful liver transplant in 1967 at the University of Colorado University Hospital.

Starzl joined the Pitt School of Medicine in 1981 as professor of surgery and led a team of surgeons who performed 30 liver transplants that year, launching the first liver transplant program in the country. Starzl’s achievements in both surgery and research have been widely credited as transforming modern medicine.

Find more information about the award on Pittwire.

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Public Health's Albert named editor of Gerontological Society's Innovation in Aging

The Gerontological Society of America — the nation’s largest interdisciplinary organization devoted to the field of aging — has named Steven M. Albert, chair of the Graduate School of Public Health’s Department of Behavioral and Community Health Sciences, as the next editor-in-chief of the journal Innovation in Aging, effective January 2021.

“We are thrilled to welcome Dr. Albert as editor-in-chief. He has a stellar career in aging research and has profound leadership and management skills that will be essential in this role,” said Ishan C. Williams, the chair of the society's Program, Publications and Products Committee. 

Innovation in Aging is an online open access journal. It contains conceptually sound, methodologically rigorous research studies that describe innovative theories, research methods, interventions, evaluations and policies relevant to aging and the life course.

“In its four years as an online journal, Innovation in Aging has already made its mark as a place for cutting-edge research,” Albert said. “It attracts high-quality research that cuts across the disparate fields of gerontology.”

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Engineering researchers receive NSF award

Nathan Youngblood and Feng Xiong, assistant professors of electrical and computer engineering, have received $380,000 from the National Science Foundation to study phase-change materials and overcome the challenges inherent in the technology, which is promising for new applications like high-speed computing and advanced optical storage.

Read more about their work

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NSF grant funds Madison's collaborative efforts to build research coordination network

Michael Madison, a professor at Pitt Law, is co-leading a novel research collaborative called The Governing Knowledge Commons Project, which received a National Science Foundation award to support efforts to build a research coordination network. 

The other co-principal investigators are Brett Frischmann, professor at Villanova University's Charles Widger School of Law; and Katherine Jo Strandburg, professor at New York University's School of Law.

This NSF-funded project will extend existing research, supporting a new network designed to build a research community to advance the work systematically and scientifically. 

This network, funded by a $350,000 grant, will assemble researchers from around the world and from law, the social and behavioral sciences, computer science, and engineering, allowing them to coordinate, integrate and communicate research across multiple disciplinary and organizational boundaries.

The project, which will take place over three years, will facilitate a series of focused working conferences, each organized around a specific subject matter, as well as a capstone convergence conference bringing the entire network and its research together.

“It’s an exciting time for knowledge commons research. IP law focuses on exclusive property rights. We’re focused on the power of collaboration. I’m thrilled by the recognition by the NSF and what these resources offer to the future of the field and to the future of technology policy,” Madison said.